Review finds human rabies cases occurring despite post‑exposure prophylaxis

Rabies remains a fatal disease transmitted from animals to humans. Post‑exposure prophylaxis (PEP) is the standard preventive treatment. The review examines cases where rabies developed despite proper PEP. It compiles documented breakthrough infections after zoonotic exposure. Findings highlight circumstances where PEP may fail. The analysis discusses potential reasons for prophylaxis failure. Implications stress the need for vigilance even after PEP. The authors recommend further research into improving preventive protocols.